Youth with autism and sensory overresponsivity show brain-based sensorilimbic hyperresponsivity and difficulty habituating to stimuli; those without overresponsivity may regulate via prefrontal downregulation of amygdala activity.
Green, S.A., Hernandez, L., Tottenham, N., Krasileva, K., Bookheimer, S.Y. & Dapretto, M. (2015). Neurobiology of sensory overresponsivity in youth with autism spectrum disorders. JAMA Psychiatry. doi: 10.1001/jamapsychiatry.2015.0737