Researchers identify a mechanism of epigenetics (gene-environment interaction) and plasticity in the brain.
Maze, I., Wenderski, W., Noh, K.M., Bagot, R.C., Tzavaras, N., Purushothaman, I., Elsässer, S.J., Guo, Y., Ionete, C., Hurd, Y.L., Tamminga, C.A., Halene, T., Farrelly, L., Soshnev, A.A., Wen, D., Rafii, S., Birtwistle, M.R., Akbarian, S., Buchholz, B.A., Blitzer, R.D., Nestler, E.J., Yuan, Z.F., Garcia, B.A., Shen, L., Molina, H., Allis, C.D. (2015). Critical role of histone turnover in neuronal transcription and plasticity. Neuron. doi:10.1016/j.neuron.2015.06.014
