Epigenetics and Neuroplasticity

Researchers identify a mechanism of epigenetics (gene-environment interaction) and plasticity in the brain.

Maze, I., Wenderski, W., Noh, K.M., Bagot, R.C., Tzavaras, N., Purushothaman, I., Elsässer, S.J., Guo, Y., Ionete, C., Hurd, Y.L., Tamminga, C.A., Halene, T., Farrelly, L., Soshnev, A.A., Wen, D., Rafii, S., Birtwistle, M.R., Akbarian, S., Buchholz, B.A., Blitzer, R.D., Nestler, E.J., Yuan, Z.F.,  Garcia, B.A., Shen, L., Molina, H., Allis, C.D. (2015). Critical role of histone turnover in neuronal transcription and plasticity. Neuron. doi:10.1016/j.neuron.2015.06.014

Epigenetic Markers of Cognitive Ability

Perinatal epigenetic processes mark later neurocognitive function and behavior.

Lillycrop, K.A.,  Costello, P.M., Teh, A.L., Murray, R.J., Clarke-Harris, R., Barton, S.J., Garratt, E.S., Ngo, S., Sheppard, A.M., Wong, J., Dogra, S., Burdge, G.C., Cooper, C., Inskip, H.M., Gale, C.R., Gluckman, P.D., Harvey, N.C., Chong, Y.S., Yap, F., Meaney, M.J., Rifkin-Graboi, A., Holbrook, J.D. & Godfrey, K.M. (2015). Association between perinatal methylation of the neuronal differentiation regulator HES1 and later childhood neurocognitive function and behaviour. International Journal of Epidemiology. doi: 10.1093/ije/dyv052